DNA replication is a fundamental biological process.The initial step in eukaryotic DNA replication is the assembly of the pre-initiation complex, including the formation of two head-to-head hexameric helicases around the replication origin.How these hexameric helicases interact with their origin dsDNA remains unknown.Here, we report the co-crystal
Immunoglobulin light chain (AL) amyloidosis LED Light Bulbs is the most common type of systemic amyloidosis in China and is associated with increased morbidity and a poor prognosis.However, the clinical characteristics of Chinese patients with AL amyloidosis have not been systematically investigated.This scoping review aimed to summarize the availa
Aim: To demonstrate the feasibility and accessibility of performing adequate mastectomy to extirpate the breast tissue, along with en-block formal axillary dissection performed from within the same incision.We also compared different methods of immediate breast reconstruction used to fill the skin envelope to achieve the best aesthetic results.Meth
Abstract The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters.LLMs have stirred up much interest among researchers and practitioners in their impressive skills in natural language processing tasks, which pro
Highly selective vagotomy accepted by increasing number of surgeons due to its low operative risk and relative lack of all side effects associated with other types of surgery like Truncal Vagotomy and drainage procedures.Our study concentrates on Blenders cases of chronic duodenal ulcer operations by H.S.V.regarding morbidity, mortality and recurre